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Invitrogen
ITGA8 Monoclonal Antibody (481709)
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ITGA8 Antibody (MA5-24196) in ICC/IF
Immunocytochemistry analysis of ITGA8 in immersion fixed H4 human neuroglioma cell line. Samples were incubated in ITGA8 monoclonal antibody (Product # MA5-24196) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces and cytoplasm.
产品信息
MA5-24196
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
481709
抗原
E. coli-derived recombinant human Integrin alpha 8 Glu610-Leu800
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGF.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: integrin alpha 8; Integrin alpha-8; integrin, alpha 8
基因别名: ITGA8
UniProt ID: (Human) P53708
Entrez Gene ID: (Human) 8516
metanephros development
kidney development
cell-matrix adhesion
integrin-mediated signaling pathway
brain development
memory
single organismal cell-cell adhesion
cell projection organization
extracellular matrix organization
positive regulation of transforming growth factor beta receptor signaling pathway
substrate adhesion-dependent cell spreading
inner ear morphogenesis
establishment of protein localization
mesodermal cell differentiation
smooth muscle tissue development
positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
