Invitrogen

ITGA9/ITGB1 Monoclonal Antibody (Y9A2)

问题与答案

问题与答案

问题与答案

产品信息

MA1-80920

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-dependent

-

免疫沉淀 (IP)

Assay-dependent

-

产品规格

种属反应

Guinea pig, Human, Pig

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

Y9A2

抗原

alpha9 integrin transfected lambda cells.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Mouse anti Human Integrin alpha 9 beta 1 antibody, clone Y9A2 recognizes the human alpha9 integrin, a approximately 140 kDa glycoprotein expressed as a heterodimer in association with the beta1 integrin.

靶标信息

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CD29; Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; integrin alpha 9; Integrin alpha-9; Integrin alpha-RLC; integrin beta 1; Integrin beta-1; integrin beta-1 subunit; Integrin beta1; integrin VLA-4 beta subunit; integrin, alpha 9; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); very late activation protein, beta polypeptide; VLA-4 subunit beta

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基因别名: ALPHA-RLC; CD29; FNRB; GPIIA; ITGA4L; ITGA9; ITGB1; MDF2; MSK12; RLC; VLA-BETA; VLAB

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UniProt ID: (Human) Q13797, (Pig) Q9GLP0, (Human) P05556

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Entrez Gene ID: (Pig) 100626707, (Human) 3680, (Pig) 397019, (Human) 3688, (Guinea pig) 100716659, (Guinea pig) 100719502

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collagen binding laminin binding metal ion binding signaling receptor activity protein heterodimerization activity virus receptor activity glycoprotein binding fibronectin binding protease binding actin binding integrin binding protein binding coreceptor activity protein kinase binding protein domain specific binding C-X3-C chemokine binding protein complex binding peptide binding cell adhesion molecule binding alpha-actinin binding collagen binding involved in cell-matrix adhesion cadherin binding involved in cell-cell adhesion integrin

cell adhesion integrin-mediated signaling pathway extracellular matrix organization neutrophil chemotaxis wound healing regulation of collagen catabolic process positive regulation of cell migration receptor internalization cell adhesion mediated by integrin cellular response to low-density lipoprotein particle stimulus positive regulation of protein localization to plasma membrane G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification tissue homeostasis cell migration involved in sprouting angiogenesis cellular calcium ion homeostasis cellular defense response homophilic cell adhesion via plasma membrane adhesion molecules leukocyte cell-cell adhesion cell-matrix adhesion calcium-independent cell-matrix adhesion transforming growth factor beta receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway positive regulation of cell proliferation negative regulation of cell proliferation germ cell migration visual learning positive regulation of cell-substrate adhesion positive regulation of neuron projection development response to activity cell migration formation of radial glial scaffolds B cell differentiation negative regulation of cell projection organization cell-substrate adhesion protein transport within lipid bilayer cell-cell adhesion mediated by integrin heterotypic cell-cell adhesion response to gonadotropin negative regulation of Rho protein signal transduction response to drug positive regulation of apoptotic process stress fiber assembly positive regulation of MAPK cascade positive regulation of GTPase activity sarcomere organization negative regulation of neuron differentiation positive regulation of endocytosis viral entry into host cell mesodermal cell differentiation axon extension dendrite morphogenesis positive regulation of peptidyl-tyrosine phosphorylation regulation of immune response leukocyte migration leukocyte tethering or rolling regulation of cell cycle cardiac muscle cell differentiation maternal process involved in female pregnancy bicellular tight junction assembly cellular response to mechanical stimulus cellular response to vitamin D cellular response to ionizing radiation positive regulation of establishment of protein localization to plasma membrane negative regulation of anoikis