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Abnova
ITM2B Polyclonal Antibody, MaxPab™
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图: 1 / 2
ITM2B Antibody (H00009445-D03P) in WB
Western Blot analysis of ITM2B expression in transfected 293T cell line (H00009445-T03) by ITM2B MaxPab polyclonal antibody.
Lane 1: ITM2B transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate.
Lane 1: ITM2B transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00009445-D03P
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ITM2B (AAH16148.1, 1 a.a. approximately 266 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MVKVTFNSAL AQKETKKDEP KSGEEALIIP PDAVAVDCKD PDDVVPVGQR RAWCWCMCFG LAFMLAGVIL GGAYLYKYFA LQPDDVYYCG IKYIKDDVIL NEPSADAPAA LYQTIEENIK IFEEEEVEFI SVPVPEFADS DPANIVHDFN KKLTAYLDLN LDKCYVIPLN TSIVMPPRNL LELLINIKAG TYLPQSYLIH EHMVITDRIE NIDHLGFFIY RLCHDKETYK LQRRETIKGI QKREASNCFA IRHFENKFAV ETLICS
靶标信息
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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