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产品信息
PA5-22342
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 222 of IVD (Uniprot ID#P26440)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11153709
产品详细信息
Recommended positive controls: HeLa, Jurkat, mouse brain, PC-12.
Predicted reactivity: Mouse (90%), Rat (90%), Pig (91%), Chicken (85%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Butyryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; isovaleryl dehydrogenase; Isovaleryl-CoA dehydrogenase, mitochondrial; IVD
基因别名: 1300016K07Rik; 6720455E18Rik; ACAD2; AI463340; IVD
UniProt ID: (Human) P26440, (Rat) P12007, (Mouse) Q9JHI5
Entrez Gene ID: (Human) 3712, (Rat) 24513, (Mouse) 56357
fatty-acyl-CoA binding
isovaleryl-CoA dehydrogenase activity
electron carrier activity
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
acyl-CoA dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
