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Invitrogen
IVNS1ABP Polyclonal Antibody
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产品信息
PA5-100582
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IVNS1ABP(Accession Q9Y6Y0), corresponding to amino acid residues T403-R453.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total IVNS1ABP.
靶标信息
IVNS1ABP is a protein coding gene involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro).; (Microbial infection) involved in the alternative splicing of influenza A virus M1 mRNA through interaction with HNRNPK, thereby facilitating the generation of viral M2 protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aryl hydrocarbon receptor-associated 3; Aryl hydrocarbon receptor-associated protein 3; Influenza virus NS1A-binding protein; Influenza virus NS1A-binding protein homolog; kelch family protein Nd1; Kelch family protein Nd1-L; kelch-like family member 39; Kelch-like protein 39; NCX downstream gene 1; ND1-L2; Nd1-S; NS1-binding protein; NS1-binding protein homolog; NS1-BP
基因别名: 1190004M08Rik; 1700126I16Rik; AA960440; ARA3; FLARA3; HSPC068; IVNS1ABP; KIAA0850; KLHL39; mKIAA0850; ND1; Nd1-L; Nd1-S; Nd1L; Nd1S; NS-1; NS1; NS1-BP; NS1BP
UniProt ID: (Human) Q9Y6Y0, (Mouse) Q920Q8
Entrez Gene ID: (Human) 10625, (Mouse) 117198, (Rat) 289089
