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Invitrogen
Immunoglobulin E protein Recombinant Mouse Monoclonal Antibody (9F12)
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Immunoglobulin E protein Antibody (MA566409) in SDS-PAGE
SDS-PAGE characterization of Immunoglobulin E protein under reducing conditions. Lane M: Protein marker (kDa); Lane IgE-C: Purified Immunoglobulin E protein Recombinant Monoclonal (Product # MA566409) (capture antibody). Lane IgE-D: Purified Immunoglobulin E protein Recombinant Monoclonal Immunoglobulin E protein (detection antibody). Gels were stained with Coomassie Brilliant Blue R-348.
产品信息
MA566409
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
9F12
抗原
IgE.
偶联物
形式
Liquid
浓度
5.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Immunoglobulin E (IgE) is a class of immunoglobulins that plays a crucial role in allergic reactions and immune responses. Structurally, IgE is similar to IgG but contains an epsilon heavy chain with a high carbohydrate content and an additional constant region (CH4). IgE antibodies are tetramers consisting of two light chains (kappa or lambda) and two epsilon-heavy chains, each with a variable region and four constant region domains. IgE is primarily found in serum and is involved in type I hypersensitivity reactions, parasitic infections, and autoimmune processes. It binds to Fc receptors Fc-epsilonRI and Fc-epsilonRII/CD23, mediating powerful effector functions. The gene encoding IgE is located on chromosome 14, and its expression is tightly regulated to prevent excessive allergic responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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