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Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 increases AKT phosphorylation in the absence and presence of insulin. ITLN1 may play a role in the defense system against microorganisms. ITLN1 may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. ITLN1 may be involved in iron metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endothelial lectin HL-1; FLJ20022; Galactofuranose-binding lectin; intelectin 1 (galactofuranose binding); Intelectin-1; Intestinal lactoferrin receptor; ITLN-1; Omentin
基因别名: hIntL; HL-1; HL1; INTL; ITLN; ITLN1; LFR; omentin; UNQ640/PRO1270
UniProt ID: (Human) Q8WWA0
Entrez Gene ID: (Human) 55600