NeoBiotechnologies

Interleukin-25 (IL-25)/IL-17E Monoclonal Antibody (IL25/625)

Name: Interleukin-25 (IL-25)\/IL-17E Monoclonal Antibody (IL25\/625)
Brand: NeoBiotechnologies
SKU: 64806-MSM1-P1

查看其他20个IL-25抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)

Interleukin-25 (IL-25)/IL-17E Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Interleukin-25 (IL-25)/IL-17E Antibody (64806-MSM1-P1) in IHC (P)

Formalin-fixed, paraffin-embedded human colon carcinoma stained with Interleukin-25 (IL-25) Mouse Monoclonal Antibody (IL25/625). HIER: Tris/EDTA, pH9.0, 45 min. 2nd Ab: HRP-polymer, 30 min. DAB, 5 min.

Interleukin-25 (IL-25)/IL-17E Antibody in Immunoelectrophoresis (IE)

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产品信息

64806-MSM1-P1

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

免疫电泳 (IE)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

IL25/625

抗原

Recombinant fragment of human IL25 protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4°C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Antibody is stable for 24 months.

Positive Control: Human brain, kidney or lung. Cellular Localization: Secreted.

Specificity Comments: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.

靶标信息

Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.

仅用于科研。不用于诊断过程。未经明确授权不得转售。