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Invitrogen
JARID2 Polyclonal Antibody
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产品信息
PA5151074
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Highest antigen sequence identity to the following orthologs: Mouse- 96%, Rat- 98%.
Sequence of this protein is as follows: LLQANGTPGL QMLESNVMIS PEVLCKEGIK VHRTVQQSGQ FVVCFPGSFV SKVCCGYSVS ETVHFATTQW TSMGFETAKE MKRR
靶标信息
Jumonji (JARID2) is a nuclear protein that participates in the negative regulation of cell growth. It is required for neural tube formation and is essential for normal heart development and function. Also, it is a part of a group of proteins characterized by a novel structural motif, the JmjC domain, which is implicated in chromatin regulation through histone demethylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: JARD2 antibody; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji-like protein; Jumonji/ARID domain-containing protein 2; Protein Jumonji; unnamed protein product
基因别名: DIDDF; JARID2; JMJ
UniProt ID: (Human) Q92833
Entrez Gene ID: (Human) 3720
negative regulation of transcription from RNA polymerase II promoter
liver development
chromatin organization
chromatin remodeling
central nervous system development
cell proliferation
regulation of gene expression
cell differentiation
regulation of cell proliferation
negative regulation of transcription, DNA-templated
spleen development
thymus development
system development
stem cell differentiation
cardiac muscle cell proliferation
negative regulation of cardiac muscle cell proliferation
random inactivation of X chromosome
facultative heterochromatin formation
protein localization to nuclear pericentric heterochromatin
cellular response to leukemia inhibitory factor
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