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NeoBiotechnologies
JAZF1 (Transcription Corepressor) Monoclonal Antibody (PCRP-JAZF1-1C2)
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产品信息
221895-MSM4-P1
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
PCRP-JAZF1-1C2
抗原
Recombinant fragment (around aa1-130) of human JAZF1 protein.
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Antibody is stable for 24 months.
Positive Control: HeLa or U87 cells.Ubiquitous tissue expression. Cellular Localization: Nucleus.
Specificity Comments: JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis.
Predicted to react in Mouse
靶标信息
JAZF1 is a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors.This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp761K2222; juxtaposed with another zinc finger gene 1; Juxtaposed with another zinc finger protein 1; TAK1-interacting protein 27; Zinc finger protein 802
基因别名: JAZF1; TIP27; ZNF802
UniProt ID: (Human) Q86VZ6
Entrez Gene ID: (Human) 221895
