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Invitrogen
JIK Polyclonal Antibody
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图: 1 / 3
JIK Antibody (PA5-116005) in ICC/IF
Immunocytochemistry analysis of JIK in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-116005). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116005
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TAOK3(Accession Q9H2K8), corresponding to amino acid residues Q534-K584.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total TAOK3.
靶标信息
TAOK3 (JIK) is a serine/threonine kinase that is a member of the GCK-like subfamily of the STE20 kinase family. JIK is ubiquitously expressed in human tissues, inhibits JNK and has been implicated in cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Axotomy-related gene 357 protein; CTCL-associated antigen HD-CL-09; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; DKFZp666H245; EC 2.7.11.1; FLJ31808; hKFC-A; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; Kinase from chicken homolog A; Serine/threonine-protein kinase TAO3; STE2-like kinase; tao; Thousand and one amino acid protein 3
基因别名: 2900006A08Rik; A130052D22; A430105I05Rik; Arg357; DPK; JIK; KDS; MAP3K18; TAOK3
UniProt ID: (Mouse) Q8BYC6, (Rat) Q53UA7
Entrez Gene ID: (Mouse) 330177, (Rat) 304530
MAPK cascade
activation of MAPKK activity
DNA repair
protein phosphorylation
cellular response to DNA damage stimulus
mitotic G2 DNA damage checkpoint
regulation of mitotic cell cycle
phosphorylation
signal transduction by protein phosphorylation
stress-activated protein kinase signaling cascade
positive regulation of stress-activated MAPK cascade
regulation of apoptotic process
positive regulation of JUN kinase activity
negative regulation of JNK cascade
positive regulation of JNK cascade
protein autophosphorylation
intracellular signal transduction
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