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Invitrogen
JMJD2A Monoclonal Antibody (5H1)
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产品信息
MA5-15678
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5H1
抗原
Purified recombinant fragment of human KDM4A expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-15678 targets KDM4A in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15678 immunogen is purified recombinant fragment of human KDM4A expressed in E. Coli.
MA5-15678 detects KDM4A which has a predicted molecular weight of approximately 120kDa.
靶标信息
JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A; JmjC domain-containing histone demethylation protein 3A; jumonji C domain-containing histone demethylase 3A; jumonji domain containing 2; jumonji domain containing 2A; Jumonji domain-containing protein 2A; lysine (K)-specific demethylase 4A; Lysine-specific demethylase 4A; tudor domain containing 14A
基因别名: JHDM3A; JMJD2; JMJD2A; KDM4A; KIAA0677; TDRD14A
UniProt ID: (Human) O75164
Entrez Gene ID: (Human) 9682
transcription, DNA-templated
negative regulation of autophagy
negative regulation of gene expression
cardiac muscle hypertrophy in response to stress
viral process
histone demethylation
negative regulation of transcription, DNA-templated
oxidation-reduction process
histone H3-K36 demethylation
negative regulation of histone H3-K9 trimethylation
