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Invitrogen
JMJD2A Recombinant Rabbit Monoclonal Antibody (K01_2Q21)
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产品信息
MA564252
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_2Q21
抗原
A synthesized peptide derived from human KDM4A/JHDM3A/JMJD2A (aa 591-607).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 40% glycerol, 150mM NaCl, 0.05% BSA
内含物
0.01% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KKSKGRRQPL SKLPRHH
靶标信息
JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A; JmjC domain-containing histone demethylation protein 3A; jumonji C domain-containing histone demethylase 3A; jumonji domain containing 2; jumonji domain containing 2A; Jumonji domain-containing protein 2A; lysine (K)-specific demethylase 4A; Lysine-specific demethylase 4A; tudor domain containing 14A
基因别名: JHDM3A; JMJD2; JMJD2A; KDM4A; KIAA0677; TDRD14A
UniProt ID: (Human) O75164
Entrez Gene ID: (Human) 9682
transcription, DNA-templated
negative regulation of autophagy
negative regulation of gene expression
cardiac muscle hypertrophy in response to stress
viral process
histone demethylation
negative regulation of transcription, DNA-templated
oxidation-reduction process
histone H3-K36 demethylation
negative regulation of histone H3-K9 trimethylation
