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Invitrogen
JRK Polyclonal Antibody
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产品信息
PA5-65735
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LELVKEGSSCP GQLRQRQAAS WGVAGREAEG GRPPAATSPA EVVWSSEKTP KADQDGGGDP GEGEEVAWEQ AAVAFDAVLR FAERQPCFSA
Highest antigen sequence identity to the following orthologs - mouse 45%, rat 46%.
靶标信息
The JRK gene encodes a protein known as JRK (Jerky) homolog, which is implicated in various cellular processes, including DNA damage response and transcription regulation. JRK is conserved across multiple species and plays a role in the stability of neuronal functions and development. It is notably associated with neuropsychiatric disorders, where aberrations in its expression or function can contribute to conditions such as epilepsy and intellectual disabilities. The protein interacts with other cellular components to influence gene expression patterns, which are critical for maintaining normal neuronal activity. JRK is also studied for its potential involvement in cancer biology, where it may impact cell cycle regulation and genomic stability. Understanding the functions and mechanisms of JRK can provide insights into its roles in both normal physiological processes and disease states, particularly in the context of the nervous system and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: jerky homolog; Jerky protein homolog; Jrk homolog
基因别名: jerky; JH8; JRK
UniProt ID: (Human) O75564
Entrez Gene ID: (Human) 8629
