Invitrogen

JunB Polyclonal Antibody

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JunB Polyclonal Antibody

产品信息

PA1-835

应用
建议稀释比
已发表文章

免疫印迹 (WB)

10 µg/mL
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免疫细胞化学 (ICC/IF)

2 µg/mL
-

免疫沉淀 (IP)

Assay-dependent
-

染色质免疫沉淀 实验 (ChIP)

1-3 µL
-

亲和纯化 (AP)

-
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产品规格

种属反应

Human, Mouse

已发表种属

C. elegans

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues D(45) P Y R G L K G P G A R G P G P E(61) of mouse JunB.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

1 mg/mL

纯化类型

IgG fraction

保存液

PBS

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2130014

产品详细信息

PA1-835 detects JunB from mouse cells.

PA1-835 has been successfully used in ChiP, Western blot and immunoprecipitation procedures. By Western blot, this antibody detects an ~38 kDa protein representing JunB from both uninduced and induced L929 cells.

The PA1-835 immunogen is a synthetic peptide corresponding to residues D(45) P Y R G L K G P G A R G P G P E(61) of mouse JunB.

Reconstitute in 200 µL PBS to create a stock of 1 mg/mL.

靶标信息

JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: activator protein 1; Jun B; jun B proto-oncogene; Jun-B oncogene; MyD21; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; transcription factor jun-B; Transcription factor JunB

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基因别名: AP-1; Jun-b; JUNB

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UniProt ID: (Human) P17275, (Mouse) P09450

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Entrez Gene ID: (Human) 3726, (Mouse) 16477

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功能
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription coactivator activity transcription corepressor activity protein binding transcription factor binding RNA polymerase II regulatory region sequence-specific DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding basic leucine zipper transcription factor
参与通路
negative regulation of transcription from RNA polymerase II promoter vasculogenesis osteoblast differentiation trophectodermal cell differentiation regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter response to radiation response to light stimulus response to mechanical stimulus regulation of cell death osteoclast differentiation response to lipopolysaccharide response to progesterone cellular response to hormone stimulus osteoblast proliferation response to cytokine regulation of cell proliferation response to drug response to peptide hormone positive regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter decidualization response to corticosterone response to cAMP regulation of cell cycle embryonic process involved in female pregnancy labyrinthine layer blood vessel development cellular response to calcium ion in utero embryonic development transcription, DNA-templated regulation of transcription, DNA-templated cellular process
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