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KARS Antibody (PA5-115527) in ICC/IF
Immunocytochemistry analysis of KARS in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115527). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-115527
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KARS(Accession Q15046), corresponding to amino acid residues A521-P571.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900163
产品详细信息
Antibody detects endogenous levels of total Lysyl tRNA synthetase.
靶标信息
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 6.1.1.6; lysine tRNA ligase; Lysine--tRNA ligase; LysRS; Lysyl-tRNA synthetase
基因别名: AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; KARS; KARS1; KARS2; KIAA0070; KRS; LysRS; mKIAA0070
UniProt ID: (Human) Q15046, (Rat) Q5XIM7, (Mouse) Q99MN1
Entrez Gene ID: (Human) 3735, (Rat) 292028, (Mouse) 85305
