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Invitrogen
KCNJ14 Polyclonal Antibody
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KCNJ14 Antibody (PA5-103645) in IHC (P)
Immunohistochemistry analysis of KCNJ14 in rat testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with KCNJ14 polyclonal antibody (Product # PA5-103645) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-103645
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KCNJ14(Accession Q9UNX9), corresponding to amino acid residues T386-P436.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total KCNJ14.
靶标信息
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+) channel Kir2.4; inwardly rectifying potassium channel KIR2.4; IRK-4; IRK4; Potassium channel, inwardly rectifying subfamily J member 14; potassium channel, inwardly rectifying subfamily J, member 14; potassium inwardly-rectifying channel J14; potassium inwardly-rectifying channel, subfamily J, member 14
基因别名: A930026G01Rik; IRK4; KCNJ14; KIR2.4
UniProt ID: (Human) Q9UNX9, (Rat) O70596, (Mouse) Q8JZN3
Entrez Gene ID: (Human) 3770, (Rat) 276720, (Mouse) 211480
