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Invitrogen
KCNK10 Polyclonal Antibody
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KCNK10 Antibody (PA5-88209) in WB
Western blot analysis of KCNK10 in extracts of various cell lines. Samples were incubated with KCNK10 Polyclonal antibody (Product # PA5-88209) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-88209
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 384-543 of human KCNK10 (NP_6121911)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RLGLDQRAHS LDMLSPEKRS VFAALDTGRF KASSQESINN RPNNLRLKGP EQLNKHGQGA SEDNIINKFG STSRLTKRKN KDLKKTLPED VQKIYKTFRN YSLDEEKKEE ETEKMCNSDN SSTAMLTDCI QQHAELENGM IPTDTKDREP ENNSLLEDRN; Positive Samples: Mouse spleen, Rat testis; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2P domain potassium channel TREK2; Outward rectifying potassium channel protein TREK-2; outward rectifying potassium channel TREK2; Potassium channel subfamily K member 10; potassium channel TREK-2; potassium channel, subfamily K, member 10; potassium channel, two pore domain subfamily K, member 10; protein phosphatase 1, regulatory subunit 97; TREK-2 K(+) channel subunit; TREK-2 two-pore-domain K+ channel; TWIK-related K+ channel 2
基因别名: 1700024D23Rik; 3010005K24Rik; K2p10.1; KCNK10; PPP1R97; TREK-2; TREK2
UniProt ID: (Human) P57789, (Rat) Q9JIS4, (Mouse) Q8BUW1
Entrez Gene ID: (Human) 54207, (Rat) 65272, (Mouse) 72258
