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Invitrogen
KCNK6 Polyclonal Antibody
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KCNK6 Antibody (PA5-116656) in WB
Western blot analysis of KCNK6 in extracts of various cell lines. Samples were incubated with KCNK6 Polyclonal antibody (Product # PA5-116656) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-116656
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
0.65 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: BxPC-3, HT-29, K-562, A-549, 293T, Mouse pancreas, Mouse heart
Immunogen sequence: QTFRHVSDLH GLTELILLPP PCPASFNADE DDRVDILGPQ PESHQQLSAS SHTDYASIPR
靶标信息
KCNK6 channels play a critical role in maintaining the electrical stability of cells, and their dysfunction can contribute to a variety of pathophysiological conditions. KCNK6, also known as TWIK-2 (Tandem of Pore Domains in a Weak Inwardly Rectifying K+ Channel 2), is a member of the two-pore-domain potassium (K2P) channel family.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ12282; Inward rectifying potassium channel protein TWIK-2; K2P6.1 potassium channel; Potassium channel subfamily K member 6; potassium channel, subfamily K, member 6; potassium channel, two pore domain subfamily K, member 6; potassium inwardly-rectifying channel, subfamily K, member 6; TWIK-2 two-pore-domain K+ channel; TWIK-originated similarity sequence; TWIK-originated sodium similarity sequence
基因别名: D7Ertd764e; K2p6.1; KCNK6; KCNK8; TOSS; TWIK-2; TWIK2
UniProt ID: (Human) Q9Y257, (Rat) G3V8R8, (Mouse) Q3TBV4
Entrez Gene ID: (Human) 9424, (Rat) 116491, (Mouse) 52150
negative regulation of systemic arterial blood pressure
potassium ion transport
stabilization of membrane potential
regulation of ion transmembrane transport
regulation of resting membrane potential
cardiac conduction
potassium ion transmembrane transport
regulation of systemic arterial blood pressure
