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Alomone Labs, LTD
KCNK6 (TWIK-2) Polyclonal Antibody
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产品信息
APC-040-200UL
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)ESHQQLSASSHTDYASIPR, corresponding to residues 295-313 of human KCNK6, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA, 5% sucrose
内含物
0.025% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
KCNK6 channels play a critical role in maintaining the electrical stability of cells, and their dysfunction can contribute to a variety of pathophysiological conditions. KCNK6, also known as TWIK-2 (Tandem of Pore Domains in a Weak Inwardly Rectifying K+ Channel 2), is a member of the two-pore-domain potassium (K2P) channel family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ12282; Inward rectifying potassium channel protein TWIK-2; K2P6.1 potassium channel; Potassium channel subfamily K member 6; potassium channel, subfamily K, member 6; potassium channel, two pore domain subfamily K, member 6; potassium inwardly-rectifying channel, subfamily K, member 6; TWIK-originated similarity sequence; TWIK-originated sodium similarity sequence
基因别名: K2p6.1; KCNK6; KCNK8; TOSS; TWIK-2; TWIK2
UniProt ID: (Human) Q9Y257, (Rat) G3V8R8
Entrez Gene ID: (Human) 9424, (Rat) 116491
negative regulation of systemic arterial blood pressure
potassium ion transport
stabilization of membrane potential
regulation of ion transmembrane transport
regulation of resting membrane potential
cardiac conduction
potassium ion transmembrane transport
regulation of systemic arterial blood pressure
