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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TCTAIHTDIM DDWLDCAFTC GVHCHGQGKY PCLQVFVNLS HPGQKALLHY NEEAVQINPK CFYTPKCHQD RNDLLNSALD IKEFFDHKNG TPFSCFYSPA SQ
Highest antigen sequence indentity to the following orthologs: Rat - 75%, Mouse - 69%.
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BK beta 3; BK channel subunit beta-3; BKbeta3; Calcium-activated potassium channel subunit beta-3; Calcium-activated potassium channel, subfamily M subunit beta-3; Charybdotoxin receptor subunit beta-3; K(VCA)beta-3; Maxi K channel subunit beta-3; Slo-beta-3; slobeta3 (KCNMB3)
Gene Aliases: KCNMB2; KCNMB3; KCNMBL
Entrez Gene ID: (Human) 27094
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