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This target displays homology in the following species: Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KCa4.1KIAA1422FLJ41282; Potassium channel subfamily T member 1; Slo2.2
基因别名: C030030G16Rik; Kcnt1; Kiaa1422; Slack; slo2; Slo2.2
UniProt ID: (Mouse) Q6ZPR4
Entrez Gene ID: (Mouse) 227632