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Invitrogen
KCTD11 Polyclonal Antibody
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KCTD11 Antibody (PA5-142626) in WB
Western Blot analysis of KCTD11 in HEK293 lysate (10 µg protein in RIPA buffer) using KCTD11 Polyclonal Antibody (Product # PA5-142626) at 1.0 µg/mL. Lane A: HEK293 lysate over expressing Human KCTD11 with DYKDDDDK tag probed with KCTD11 Antibody. Lane B: Mock-transfected HEK293 probed with KCTD11 Antibody. Lane C: HEK293 lysate over expressing Human KCTD11 with DYKDDDDK tag probed with anti-DYKDDDDK Tag (1:5,000). Primary incubations were for 1 hour. Detected by chemiluminescence.
产品信息
PA5-142626
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-PEVEYGRLGLQP.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
靶标信息
Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BTB/POZ domain-containing protein KCTD11; KCASH1 protein; potassium channel tetramerisation domain containing 11; Potassium channel tetramerization domain-containing protein 11; retinoic acid, EGF, NGF induced gene protein; retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domain containing 11; RING-type E3 ubiquitin transferase subunit KCTD11
基因别名: C17orf36; KCASH1; KCTD11; REN; REN/KCTD11
UniProt ID: (Human) Q693B1
Entrez Gene ID: (Human) 147040
