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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SSYNYGSEDQ AEFLCVVSKE LHSTPNGLSS ESSRKTKSTE EQLEEQQQQE EEVEEVEVEQ VQVEADAQEK AQS
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 73%.
Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).
仅用于科研。不用于诊断过程。未经明确授权不得转售。