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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • KDEL Receptor Pan Antibodies

          Invitrogen

          KDEL Receptor Pan Monoclonal Antibody (KR-10)

          1 篇参考文献
          查看其他2个KDEL Receptor Pan抗体

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          Cite KDEL Receptor Pan Monoclonal Antibody (KR-10)

          KDEL Receptor Pan Monoclonal Antibody (KR-10)

          产品信息

          MA1-90944

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:1,000
          查看1篇已发表文章 1篇已发表文章

          免疫细胞化学 (ICC/IF)

          1:1,000
          -

          免疫沉淀 (IP)

          1:500
          -
          产品规格

          种属反应

          Bovine, Dog, Chicken, Fruit fly, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat, Xenopus

          已发表种属

          Human

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          KR-10

          抗原

          Peptide corresponding to aa 192-212 of bovine KDEL receptor conjugated to KLH.
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein G

          保存液

          PBS, pH 7.4

          内含物

          0.09% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_1956085

          产品详细信息

          Store as a concentrated solution. Centrifuge briefly prior to opening vial.

          靶标信息

          Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          生物信息学

          蛋白别名: (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; CG5183-PA; CG5183-PB; CG5183-PC; ELP-1; ER lumen protein retaining receptor; ER lumen protein retaining receptor 1; ER lumen protein retaining receptor 2; ER lumen protein retaining receptor 3; ER lumen protein-retaining receptor; ER lumen protein-retaining receptor 1; ER lumen protein-retaining receptor 2; ER lumen protein-retaining receptor 3; ERD-2-like protein; ERD2-like protein 1; ERD23; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; KDEL endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 2; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor 1; KDEL receptor 2; KDEL receptor 3; KDEL receptor-like protein; KDEL-receptor; KdelR-PA; KdelR-PB; KdelR-PC; lethal (2) 31Em; Putative MAPK-activating protein PM23

          查看更多 收起

          基因别名: 1110007A14Rik; 8030486F04Rik; AI173274; AW215843; BEST:CK00230; CG5183; CK00230; Dmel\CG5183; Dmel_CG5183; dmErd2; ELP-1; ERD2; ERD2.1; ERD2.2; ERD23; ERD2L3; ergr15; HDEL; I79_001653; I79_020931; I79_023963; KDELR; KDELR1; KDELR2; KDELR3; l(2)31Em; l(2)k00311; PM23; RCJMB04_8l23; XELAEV_18045328mg

          查看更多 收起

          UniProt ID: (Bovine) P33946, (Human) P24390, (Bovine) Q2KJ37, (Human) P33947, (Chicken) Q5ZKX9, (Human) O43731, (Fruit fly) O76767, (Mouse) Q99JH8, (Rat) Q569A6, (Mouse) Q9CQM2, (Rat) Q5U305, (Mouse) Q8R1L4, (Xenopus) Q7ZXS5

          查看更多 收起

          Entrez Gene ID: (Pig) 100520962, (Bovine) 618184, (Sheep) 101122047, (Human) 10945, (Dog) 484406, (Rabbit) 100349892, (Pig) 100625446, (Bovine) 531676, (Human) 11014, (Chicken) 771927, (Dog) 612839, (Sheep) 101116624, (Rabbit) 100338871, (Chicken) 418026, (Rabbit) 100338388, (Dog) 474509, (Pig) 100514523, (Sheep) 101121418, (Bovine) 509687, (Human) 11015, (Fruit fly) 34427, (Chinese hamster) 100750912, (Mouse) 68137, (Rat) 361577, (Mouse) 66913, (Rat) 304290, (Chinese hamster) 100765889, (Mouse) 105785, (Chinese hamster) 100750636, (Rat) 315131, (Xenopus) 380330

          查看更多 收起

          功能
          KDEL sequence binding ER retention sequence binding molecular_function membrane trafficking regulatory protein
          参与通路
          T cell cytokine production retrograde vesicle-mediated transport, Golgi to ER protein transport T cell differentiation T cell apoptotic process protein retention in ER lumen intracellular protein transport ER to Golgi vesicle-mediated transport IRE1-mediated unfolded protein response transport biological_process vesicle-mediated transport
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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