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Invitrogen
KELL Polyclonal Antibody
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产品信息
PA5-139866
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PRPCETSVCL DLRDHYLASG NTSVAPCTDF FSFACGRAKE TNNSFQELAT KNKNRLRRIL EVQNSWHPGS GEEKAFQFYN SCMDTLAIEA AGTGPLRQVI EELGGWRISG KWT
Highest antigen sequence indentity to the following orthologs: Rat - 70%, Mouse - 73%.
靶标信息
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bloodgroup KEL protein; CD238; KEL1 antigen; Kell blood group antigen; Kell blood group glycoprotein; Kell blood group protein; Kell blood group, metallo-endopeptidase; Kell glycoprotein; unnamed protein product; zinc-dependent metalloproteinase responsible for endothelin-3-converting vasoconstrictor activity
基因别名: CD238; ECE3; KEL; Kell
UniProt ID: (Human) P23276
Entrez Gene ID: (Human) 3792
proteolysis
cellular calcium ion homeostasis
regulation of cell size
cellular magnesium ion homeostasis
protein processing
regulation of axon diameter
vasoconstriction
myelination
skeletal muscle fiber development
establishment of localization in cell
potassium ion transmembrane transport
negative regulation of potassium ion transmembrane transport
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