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Invitrogen
KHDRBS3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-51392
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KHDRBS3. Recombinant protein control fragment (Product #RP-93687).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GEGKDEEKYI DVVINKNMKL GQKVLIPVKQ FPKFNFVGKL LGPRGNSLKR LQEETLTKMS ILGKGSMRDK AKEEELRKSG EAKYFHLNDD LHVLIEVFAP PAEAYARM
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: etoile; etoile, Sam68-like protein SLM-2; KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein Etoile; RNA-binding protein T-Star; rSLM-2; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; SLM-2
Gene Aliases: Etle; KHDRBS3; SALP; SLM-2; SLM2; T-STAR
UniProt ID: (Rat) Q9JLP1, (Mouse) Q9R226
Entrez Gene ID: (Rat) 64015, (Mouse) 13992
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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