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Invitrogen
KHDRBS3 Polyclonal Antibody
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产品信息
PA5-51392
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.10 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GEGKDEEKYI DVVINKNMKL GQKVLIPVKQ FPKFNFVGKL LGPRGNSLKR LQEETLTKMS ILGKGSMRDK AKEEELRKSG EAKYFHLNDD LHVLIEVFAP PAEAYARM
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
靶标信息
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: etoile; etoile, Sam68-like protein SLM-2; KH domain containing, RNA binding, signal transduction associated 3; KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein Etoile; RNA-binding protein T-Star; rSLM-2; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; Sam68-like phosphotyrosine protein, T-STAR; SLM-2
基因别名: Etle; etoile; KHDRBS3; SALP; SLM-2; SLM2; T-STAR; TSTAR
UniProt ID: (Human) O75525, (Rat) Q9JLP1, (Mouse) Q9R226
Entrez Gene ID: (Human) 10656, (Rat) 64015, (Mouse) 13992
