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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDNAEAQFTT ALRLTNHQEL WAFIVTNLAS VYIREGNRHQ ELYSLLERIN PDHSFPVSSH CLRAAAFYVR GLFSFFQGRY NEAKRFLRET LKMSNAEDLN RLTACSLVLL GHIFYVLGNH RESNNMVVPA MQLASKIPDM SVQLWSSALL RDLNKACGNA MDAHEAAQMH QNFSQQLLQD HIEACSLPEH NLITWTDGPP PVQFQAQNGP NTSLASLL
Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with NIPBL/SCC2 which mediates the loading of the cohesin complex onto chromatin (PubMed:28167679, PubMed:22628566). Plays a role in sister chromatid cohesion and normal progression through prometaphase (PubMed:16802858, PubMed:16682347). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cohesin loading complex subunit SCC4 homolog; MAU-2; MAU2 chromatid cohesion factor homolog
基因别名: KIAA0892; MAU2; SCC4
Entrez Gene ID: (Human) 23383