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KIAA1967 Monoclonal Antibody (4E6)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00057805-M04
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
4E6
抗原
KIAA1967 (AAH18269, 5 a.a. approximately 365 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: LPEKVVSPPE PEKEEAAKEE ATKEEEAIKE EVVKEPKDEA QNEGPATESE APLKEDGLLP KPLSSGGEEE EKPRGEASED LCEMALDPEL LLLRDDGEEE FAGAKLEDSE VRSVASNQSE MEFSSLQDMP KELDPSAVLP LDCLLAFVFF DANWCGYLHR RDLERILLTL GIRLSAEQAK QLVSRVVTQN ICQYRSLQYS RQEGLDGGLP EEVLFGNLDL LPPPGKSTKP GAAPTEHKAL VSHNGSLINV GSLLQRAEQQ DSGRLYLENK IHTLELKLEE SHNRFSATEV TNKTLAAEMQ ELRVRLAEAE ETARTAERQK SQLQRLLQEL RRRLTPLQLE IQRVVEKADS WVEKEEPAPS N
靶标信息
DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell division cycle and apoptosis regulator protein 2; DBC.1; DBCCR1; deleted in breast cancer 1; FAM5A; putative protein from MH0802201; unnamed protein product
基因别名: DBC-1; DBC1; KIAA1967; NET35; p30 DBC; p30DBC
UniProt ID: (Human) Q8N163
Entrez Gene ID: (Human) 57805
regulation of transcription, DNA-templated
RNA splicing
response to UV
negative regulation of cell growth
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of DNA-templated transcription, elongation
regulation of circadian rhythm
positive regulation of apoptotic process
negative regulation of catalytic activity
regulation of RNA splicing
mitochondrial fragmentation involved in apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of canonical Wnt signaling pathway
regulation of protein deacetylation
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of DNA damage checkpoint
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
