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Invitrogen
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Immunogen sequence: SAQCLPETLS TLRYASRAQR VTTRPQAPKS PVAKQPQRLE TEMLQLQEEN RRLQFQLDQM DCKASGLSGA RVAWAQRNLY GML
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 78%.
KIF12 encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Kinesin-like protein KIF12; RP1156P10.3
基因别名: KIF12
UniProt ID: (Human) Q96FN5
Entrez Gene ID: (Human) 113220