Abnova

KIF2 Monoclonal Antibody (2D4)

Name: KIF2 Monoclonal Antibody (2D4)
Brand: Abnova
SKU: H00003796-M01

查看其他7个KIF2A抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image KIF2 Monoclonal Antibody (2D4)

产品信息

H00003796-M01

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

免疫组化（石蜡） (IHC (P))

3 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

2D4

抗原

KIF2 (AAH31828.1, 1 a.a. approximately 679 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunogen sequence: MVTSLNEDNE SVTVEWIENG DTKGKEIDLE SIFSLNPDLV PDEEIEPSPE TPPPPASSAK VNKIVKNRRT VASIKNDPPS RDNRVVGSAR ARPSQFPEQS SSAQQNGSVS DISPVQAAKK EFGPPSRRKS NCVKEVEKLQ EKREKRRLQQ QELREKRAQD VDATNPNYEI MCMIRDFRGS LDYRPLTTAD PIDEHRICVC VRKRPLNKKE TQMKDLDVIT IPSKDVVMVH EPKQKVDLTR YLENQTFRFD YAFDDSAPNE MVYRFTARPL VETIFERGMA TCFAYGQTGS GKTHTMGGDF SGKNQDCSKG IYALAARDVF LMLKKPNYKK LELQVYATFF EIYSGKVFDL LNRKTKLRVL EDGKQQVQVV GLQEREVKCV EDVLKLIDIG NSCRTSGQTS ANAHSSRSHA VFQIILRRKG KLHGKFSLID LAGNERGADT SSADRQTRLE GAEINKSLLA LKECIRALGR NKPHTPFRAS KLTQVLRDSF IGENSRTCMI ATISPGMASC ENTLNTLRYA NRVKELTVDP TAAGDVRPIM HHPPNQIDDL ETQWGVGSSP QRDDLKLLCE QNEEEVSPQL FTFHEAVSQM VEMEEQVVED HRAVFQESIR WLEDEKALLE MTEEVDYDVD SYATQLEAIL EQKIDILTEL RDKVKSFRAA LQEEEQASKQ INPKRPRAL

靶标信息

KIF2A, a gene encoding the kinesin family member 2A protein, plays a pivotal role in neuronal development and function. This gene is part of the kinesin-13 subfamily, characterized by its unique ability to depolymerize microtubules, which are essential components of the cytoskeleton responsible for maintaining cell shape, enabling motility, and facilitating intracellular transport. KIF2A is particularly significant in neural settings, where it regulates microtubule dynamics crucial for neuronal migration and dendritic development. Dysfunctional KIF2A, due to mutations, has been linked to early-onset neurodegenerative diseases such as progressive microcephaly and mental disabilities due to impaired microtubule regulation, reflecting its foundational role in correct brain development and architecture. Additionally, KIF2A is involved in spindle assembly and chromosome segregation during cell division, further cementing its importance in both neurodevelopment and general cellular functions.

仅用于科研。不用于诊断过程。未经明确授权不得转售。