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Abnova
KIF5B Monoclonal Antibody (2A11)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00003799-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A11
抗原
KIF5B (NP_004512.1, 864 a.a. approximately 962 a.a) partial recombinant protein with GST-pstS1 tag.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: EKRLRATAER VKALESALKE AKENASRDRK RYQQEVDRIK EAVRSKNMAR RGHSAQIAKP IRPGQHPAAS PTHPSAIRGG GAFVQNSQPV AVRGGGGKQ
靶标信息
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: conventional kinesin heavy chain; epididymis secretory protein Li 61; kinesin 1 (110-120kD); kinesin heavy chain; U-KHC; ubiquitous kinesin heavy chain; unnamed protein product
基因别名: HEL-S-61; KINH; KNS; KNS1; UKHC
UniProt ID: (Human) P33176
Entrez Gene ID: (Human) 3799
microtubule-based movement
axon guidance
positive regulation of synaptic transmission, GABAergic
lysosome localization
stress granule disassembly
natural killer cell mediated cytotoxicity
regulation of membrane potential
positive regulation of potassium ion transport
vesicle transport along microtubule
synaptic vesicle transport
centrosome localization
anterograde dendritic transport of neurotransmitter receptor complex
regulation of modification of synapse structure, modulating synaptic transmission
anterograde axonal protein transport
positive regulation of protein localization to plasma membrane
anterograde neuronal dense core vesicle transport
retrograde neuronal dense core vesicle transport
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
