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Invitrogen
KIRREL2 Polyclonal Antibody
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FIGURE: 1 / 1
KIRREL2 Antibody (PA5-89009) in WB
Western blot analysis of KIRREL2 in extracts of various cell lines. Samples were incubated with KIRREL2 Polyclonal antibody (Product # PA5-89009) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-89009
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human KIRREL2 (NP_9546493)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
4.9 mg/mL
Amount
490 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GPSPHFLQQP EDLVVLLGEE ARLPCALGAY WGLVQWTKSG LALGGQRDLP GWSRYWISGN AANGQHDLHI RPVELEDEAS YECQATQAGL RSRPAQLHVL VPPEAPQVLG GPSVSLVAGV PANLTCRSRG DARPTPELLW FRDGVLLDGA TFHQTLLKEG TPGSVESTLT LTPFSHDDGA TFVCRARSQA LPTGRDTAIT; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp564A1164; Kin of IRRE-like protein 2; kin of irregular chiasm-like 2; Kin of irregular chiasm-like protein 2; MGC15718; nephrin-like 3; X kin of IRRE like 2
Gene Aliases: C330019F22Rik; Kirrel2; NEPH3; NLG1
UniProt ID: (Mouse) Q7TSU7
Entrez Gene ID: (Rat) 100359836, (Mouse) 243911
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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