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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • KLC1 Antibodies

          Invitrogen

          KLC1 Polyclonal Antibody

          查看其他15个KLC1抗体

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          Cite KLC1 Polyclonal Antibody

          • 抗体检测数据 (1)
          KLC1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          KLC1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          图: 1 / 1

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          KLC1 Antibody (PA5-96356) in WB

          Western blot analysis of KLC1 in extracts of various cell lines. Samples were incubated with KLC1 Polyclonal antibody (Product # PA5-96356) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          KLC1 Antibody in Western Blot (WB)
          KLC1 Polyclonal Antibody

          产品信息

          PA5-96356

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:2,000
          -

          免疫组化(石蜡) (IHC (P))

          1:50-1:200
          -

          酶联免疫吸附实验 (ELISA)

          1 µg/mL
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          Recombinant fusion protein containing a sequence corresponding to amino acids 261-560 of human Kinesin light chain 1 (Kinesin light chain 1 (KLC1)) (NP_0055432)
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1.11 mg/mL

          纯化类型

          Affinity Chromatography

          保存液

          PBS, pH 7.3, with 50% glycerol

          内含物

          0.02% sodium azide

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2808158

          产品详细信息

          Immunogen sequence: LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE EVSMSVEWNG MRKMKLGLVN; Positive Samples: SW480, 22Rv1, BT-474, MCF7, Mouse brain; Cellular Location: Cell projection, Cytoplasm, Cytoplasmic vesicle, cytoskeleton, growth cone

          靶标信息

          Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: kinesin 2; kinesin 2 60/70kDa; Kinesin light chain 1; Kinesin2; KLC 1; KNS 2; KNS 2A; medulloblastoma antigen MU-MB-2.50; MGC15245

          查看更多 收起

          基因别名: AI874768; KLC; KLC1; KNS2; KNS2A

          查看更多 收起

          UniProt ID: (Human) Q07866, (Rat) P37285

          查看更多 收起

          Entrez Gene ID: (Human) 3831, (Mouse) 16593, (Rat) 171041

          查看更多 收起

          功能
          motor activity microtubule motor activity protein binding tubulin binding cytoskeletal protein microtubule binding motor protein microtubule or microtubule-binding cytoskeletal protein
          参与通路
          retrograde vesicle-mediated transport, Golgi to ER microtubule-based movement viral process antigen processing and presentation of exogenous peptide antigen via MHC class II stress granule disassembly intracellular protein transport axo-dendritic transport protein localization to synapse metabolic process
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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