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Abnova
KLF1 Monoclonal Antibody (1E4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00010661-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E4
抗原
KLF1 (NP_006554, 183 a.a. approximately 237 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: PRTGLSVPAA SGAPYGLLSG YPAMYPAPQY QGHFQLFRGL QGPAPGPATS PSFLS
靶标信息
KLF1 is a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant Inblood phenotype.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: erythroid krueppel-like transcription factor; erythroid Kruppel-like factor; erythroid-specific transcription factor EKLF; Kruppel like factor 1
基因别名: CDAN4A; CDAN4B; EKLF; EKLF/KLF1
UniProt ID: (Human) Q13351
Entrez Gene ID: (Human) 10661
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
ubiquitin binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
erythrocyte differentiation
protein destabilization
positive regulation of transcription, DNA-templated
maternal process involved in female pregnancy
cellular response to endothelin
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
