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Invitrogen
KLHL21 Polyclonal Antibody
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产品信息
PA5-31730
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human KLHL21. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.84 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A549, HeLa, Jurkat, Raji.
Predicted reactivity: Mouse (95%), Rat (94%), Xenopus laevis (80%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: kelch-like family member 21; Kelch-like protein 21; MGC99635
基因别名: KIAA0469; KLHL21
UniProt ID: (Human) Q9UJP4
Entrez Gene ID: (Human) 9903
