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Immunogen sequence: AKEQIVKQNL KCRDLLDEAR NYHLHLSSRA VPDFEYSIRT TPRKHTAGVL FCVGGRGGSG DPFRSIECYS INKNSWFFGP EMNSRRRHVG VISVEGKVYA VGGHDGNEHL GSMEMFDPLT NKWMMKASMN TKRRGIALAS LGGPIYAIGG LDDNTCFNDV ERYDIESDQW STVAPMNTPR GGVGSVALVN HVYAVGGNDG MASLSSVERY DPHLDKWIEV KEMGQRRAGN GVSKLHGCLY VVGGFDDNSP LSSVERYDPR SNKWDYVAAL TTPRGGVGIA TVMGKIFAVG GHNGNAYLNT VEAFDPVLNR WELVGSVSHC RAGAGVAVCS CLTSQIRDVG HGSNNVVDCM; Positive Samples: 293T, Mouse brain, Mouse kidney, Rat thymus
Kelch-like protein 8 is a protein that in humans is encoded by the KLHL8 gene. The mRNA contains a repetitive element in its 3-prime UTR, and the deduced 451-amino acid protein shares 36% identity with the actin-binding protein MAYVEN. RT-PCR ELISA detected highest expression in adult brain, liver, skeletal muscle, kidney, and ovary, and in several specific brain regions, predominantly amygdala and thalamus. Moderate expression was detected in all other adult and fetal tissues examined.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: kelch-like 8; kelch-like family member 8; Kelch-like protein 8
基因别名: 2310001P09Rik; D5Ertd431e; KIAA1378; KLHL8
UniProt ID: (Human) Q9P2G9, (Mouse) P59280
Entrez Gene ID: (Human) 57563, (Rat) 289457, (Mouse) 246293