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Invitrogen
KLRC4 Polyclonal Antibody
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产品信息
PA5-120301
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-55 of human KLRC4 (NP_038459.1).
偶联物
形式
Liquid
浓度
2.03 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: A-549, NCI-H460, 293T, Mouse lung, Mouse kidney, Rat kidney. The target is usually found in the following locations: Membrane, Single-pass type II membrane protein.
Immunogen sequence: MNKQRGTYSE VSLAQDPKRQ QRKLKGNKIS ISGTKQEIFQ VELNLQNASS DHQGN
靶标信息
The KLRC4 (Killer Cell Lectin Like Receptor C4) gene encodes a member of the NKG2 family of receptors, which are expressed mostly on natural killer (NK) cells and some T lymphocytes. This gene is located on chromosome 12 and plays a key role in immune surveillance and the activation of NK cells. The KLRC4 protein, also known as NKG2F, interacts with other receptors such as KLRK1 (NKG2D) to recognize stress-induced ligands on potential target cells, thereby mediating their destruction. Variants and polymorphisms in KLRC4 have been investigated in various immune-related conditions, including their association with thyroid diseases and cancer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; NK cell receptor F; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor
基因别名: KLRC4; NKG2-F; NKG2F
UniProt ID: (Human) O43908
Entrez Gene ID: (Human) 8302
