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Abnova
KLRC4 Monoclonal Antibody (1D10)
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产品信息
H00008302-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1D10
抗原
KLRC4 (AAH17784, 1 a.a. approximately 158 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MNKQRGTYSE VSLAQDPKRQ QRKLKGNKIS ISGTKQEIFQ VELNLQNASS DHQGNDKTYH CKGLLPPPEK LTAEVLGIIC IVLMATVLKT IVLIPCIGVL EQNNFSLNRR MQKARHCGHC PEEWITYSNS CYYIGKERRT WEERVCWPVL RRTLICFL
靶标信息
The KLRC4 (Killer Cell Lectin Like Receptor C4) gene encodes a member of the NKG2 family of receptors, which are expressed mostly on natural killer (NK) cells and some T lymphocytes. This gene is located on chromosome 12 and plays a key role in immune surveillance and the activation of NK cells. The KLRC4 protein, also known as NKG2F, interacts with other receptors such as KLRK1 (NKG2D) to recognize stress-induced ligands on potential target cells, thereby mediating their destruction. Variants and polymorphisms in KLRC4 have been investigated in various immune-related conditions, including their association with thyroid diseases and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; NK cell receptor F; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor
基因别名: KLRC4; NKG2-F; NKG2F
UniProt ID: (Human) O43908
Entrez Gene ID: (Human) 8302
