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KRT84 Antibody (MA5-27415) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded carcinoma of human spleen tissue. To expose target proteins, heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min. Following antigen retrieval, tissues were probed with a KRT84 monoclonal antibody (Product # MA5-27415) at a dilution of 1:500.
产品信息
MA5-27415
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2D1
抗原
Full length human recombinant protein of KRT84 produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2724574
靶标信息
The Keratin multigene family is made of "soft" epithelial cytokeratins and "hard" hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.
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生物信息学
蛋白别名: hard keratin, type II, 4; K84; keratin 84, type II; keratin, hair, basic, 4; Keratin, type II cuticular Hb4; Keratin-84; type II hair keratin 4; Type II hair keratin Hb4; Type-II keratin Kb24
基因别名: HB4; KRT84; KRTHB4
UniProt ID: (Human) Q9NSB2
Entrez Gene ID: (Human) 3890
