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Invitrogen
Kinesin 5C Polyclonal Antibody
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产品信息
PA1-644
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic Peptide: C A(938) V H A I R G G G G S S S N S T H Y Q K(957)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-644 detects kinesin 5C from human samples. This antibody is specific for kinesin 5C and does not detect other kinesin isotypes. No cross-reactivity is observed using bovine or mouse samples.
PA1-644 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~110 kDa protein representing kinesin 5C from human retinal extract. An unidentified band is also detected at ~100 kDa.
The PA1-644 immunizing peptide corresponds to amino acid residues 938-957 from human kinesin 5C. This peptide (Cat. # PEP-199) is available for use in neutralization and control experiments.
靶标信息
Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Kinesin heavy chain isoform 5C; Kinesin heavy chain neuron-specific 2; Kinesin-1
基因别名: CDCBM2; KIAA0531; KIF5C; KINN; NKHC; NKHC-2; NKHC2
UniProt ID: (Human) O60282
Entrez Gene ID: (Human) 3800
