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Antibodies Inc
Kv2.1 K+ Channel Monoclonal Antibody (K89/34)
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图: 1 / 8
Kv2.1 K+ Channel Antibody (75-014) in ICC/IF
Representative maximum intensity projections from Wild-Type (WT) (black) and NPC1I1061T (red) cortical sagittal sections stained with Hoechst and immunolabeled for KV2.1 (Product # 75-014, 10 µg/mL). Right, quantification of Kv2.1 total intensity, cluster size and cluster density of WT (black) and NPC1I1061T (red) neurons in the soma region. Image from publication CC-BY-4.0. PMID:37507375.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
75-014
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
K89/34
抗原
Synthetic peptide amino acids 837-853 of rat Kv2.1 (accession number P15387).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: HMLPGGGAHG STRDQSI
靶标信息
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Delayed rectifier potassium channel 1; DRK1; KCB1; mShab; potassium channel Kv2.1; potassium voltage gated channel, Shab-related subfamily, member 1; Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel subunit Kv2.1
基因别名: DRK1PC; KCNB1; Kcr1-1; Kv2.1; Shab
UniProt ID: (Mouse) Q03717, (Rat) P15387
Entrez Gene ID: (Mouse) 16500, (Rat) 25736
SNARE binding
ion channel activity
voltage-gated ion channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
potassium channel activity
protein binding
outward rectifier potassium channel activity
ubiquitin-like protein binding
ion channel binding
protein heterodimerization activity
protein N-terminus binding
voltage-gated ion channel
action potential
transport
ion transport
potassium ion transport
vesicle docking involved in exocytosis
glutamate receptor signaling pathway
positive regulation of norepinephrine secretion
cellular response to nutrient levels
positive regulation of catecholamine secretion
regulation of ion transmembrane transport
glucose homeostasis
positive regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
protein oligomerization
protein homooligomerization
transmembrane transport
cellular response to glucose stimulus
potassium ion transmembrane transport
positive regulation of protein targeting to membrane
regulation of action potential
regulation of motor neuron apoptotic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
