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Antibodies Inc
Kv3.2 Potassium Channel Monoclonal Antibody (N410/17), FL490
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产品信息
75-397-FL490
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N410/17
抗原
Fusion protein amino acids 474-613 (cytoplasmic C-terminus) of rat Kv3.2a (accession number P22462-3) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
491/515 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Potassium channel voltage-gated Shaw-related subfamily C member 2; potassium channel, voltage gated Shaw related subfamily C, member 2; potassium voltage gated channel, Shaw-related subfamily, member 2; Potassium voltage-gated channel subfamily C member 2; potassium voltage-gated channel, Shaw-related subfamily, member 2; Shaw-like potassium channel; Voltage-gated potassium channel KCNC2; Voltage-gated potassium channel Kv3.2; Voltage-gated potassium channel subunit Kv3.2
基因别名: AW047325; B230117I07; KCNC2; KShIIIA; KV3.2
UniProt ID: (Human) Q96PR1, (Rat) P22462, (Mouse) Q14B80
Entrez Gene ID: (Human) 3747, (Rat) 246153, (Mouse) 268345
response to light intensity
response to organic cyclic compound
response to amine
globus pallidus development
response to magnesium ion
nitric oxide-cGMP-mediated signaling pathway
response to ethanol
regulation of insulin secretion
protein homooligomerization
protein heterooligomerization
cellular response to ammonium ion
cellular response to nitric oxide
potassium ion transmembrane transport
cellular response to toxic substance
positive regulation of potassium ion transmembrane transport
response to nerve growth factor
action potential
response to toxic substance
ion transmembrane transport
transport
ion transport
potassium ion transport
regulation of ion transmembrane transport
transmembrane transport
