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Invitrogen
L1RE1 Recombinant Rabbit Monoclonal Antibody (K01_2N11)
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产品信息
MA564112
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_2N11
抗原
Recombinant protein of human LINE-1 ORF1p.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 0.05% BSA, 40% glycerol, 150mM NaCl
内含物
0.01% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
L1RE1 encodes a nucleic acid-binding protein, which is essential for retrotransposition of LINE-1 elements in the genome. The proteins act as nucleic acid chaperones binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded. Long interspersed element-1/LINE-1/L1 retrotransposons are present in more than 500'000 full (6 kb) or truncated copies in the human genome. Most of them are inactive but one estimate is that 80 to 100 of those elements could be transcribed, translated and active in any individual. An active LINE-1 encodes for 2 proteins translated from a single RNA containing two non-overlapping ORFs, ORF1 and ORF2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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