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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KKEPYCRGLM AIDCPHTGIV DYRQVALSFA QDFQEAGGSV LTNFEVKGIE MAKESPSRSI DGMQYPIVIK NTKGEEI
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 78%.
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Duranin; FLJ12618; L-2-hydroxyglutarate dehydrogenase, mitochondrial
基因别名: C14orf160; L2HGDH
Entrez Gene ID: (Human) 79944