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Invitrogen
LAPTM4B Monoclonal Antibody (CL5289)
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LAPTM4B Antibody (MA5-31417) in ICC/IF
Immunofluorecent analysis of LAPTM4B in A-431 cells using LAPTM4B Monoclonal Antibody (CL5289) (Product # MA5-31417). Staining shows specific staining in vesicles and the golgi apparatus in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
产品信息
MA5-31417
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CL5289
抗原
Synthetic peptide corresponding to Human LAPTM4B
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EYIRQLPPNF PYRDD
Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 93%.
靶标信息
LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: lysosomal associated protein transmembrane 4 beta; Lysosomal-associated transmembrane protein 4B; Lysosome-associated transmembrane protein 4-beta
基因别名: LAPTM4B; LAPTM4beta; LC27; PSEC0001
UniProt ID: (Human) Q86VI4
Entrez Gene ID: (Human) 55353
