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Invitrogen
LAR4B Polyclonal Antibody
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产品信息
PA5-69095
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of mouse LAR4B
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 85%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 85%; Pig: 86%; Rabbit: 86%; Rat: 92%
靶标信息
The LAR4B gene, more accurately referred to as LARP4B (La Ribonucleoprotein Domain Family Member 4B), is associated with RNA-binding proteins that are crucial for various aspects of RNA metabolism, including RNA stabilization, translation, and cellular stress responses. LARP4B belongs to the La-related protein family, which plays significant roles in maintaining RNA stability and enhancing translation efficiency of certain mRNAs. It has been identified as a target in cancer research due to its involvement in tumor biology, particularly regulating tumor suppressive pathways and interacting with microRNA networks. Studies have shown that LARP4B expression is downregulated in prostate cancer tissues, indicating its potential role as a tumor suppressor. Moreover, it is linked with liver cancer and survival rates, reflecting its importance in cellular growth and proliferation. The regulation of LARP4B and its interactions with other cellular components underline its potential therapeutic implications for cancer treatment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: La ribonucleoprotein domain family member 4B; La ribonucleoprotein domain family member 5; La ribonucleoprotein domain family, member 5; La-related protein 4B; La-related protein 5
基因别名: A630096F19; AI256361; D13Wsu64e; Kiaa0217; Larp4b; Larp5
UniProt ID: (Mouse) Q6A0A2
Entrez Gene ID: (Mouse) 217980
