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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: FKSEDNNTED LKVTITKAGR KDDSTLCCWR HSTTEVSCQN QEYLFVYGGR SVVEPVLSDW HFLHVGTMAW VRIPVEGEVP EARHS
Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 68%.
TYW4 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW4 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Leucine carboxyl methyltransferase 2; tRNA wybutosine-synthesizing protein 4; tRNA yW-synthesizing protein 4; tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase
基因别名: KIAA0547; LCMT2; TYW4
Entrez Gene ID: (Human) 9836