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Invitrogen
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Immunogen sequence: SIWDVFTHSGK GKVLGNETAD VACDGYYKVQ EDIILLRELH VNHYRFSLSW
Highest antigen sequence identity to the following orthologs - mouse 75%, rat 71%.
This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KL lactase phlorizin hydrolase; klotho gamma; Klotho/lactase-phlorizin hydrolase-related protein; lactase-like; Lactase-like protein
基因别名: KLG; KLPH; LCTL; UNQ3022/PRO9820
UniProt ID: (Human) Q6UWM7
Entrez Gene ID: (Human) 197021