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Agrisera
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Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana (recombinant LEA6)
LEA6 encodes a small, highly hydrophilic late embryogenesis abundant (LEA) family 6 protein that accumulates predominantly in seeds during late embryogenesis and shortly after imbibition, and is also induced by water-deficit-related signals. In Arabidopsis, LEA6 family members are encoded by compact, nuclear-genome loci and produce proteins in the low-molecular-mass range typical of LEA6 (about 7-14 kDa) that are enriched in disorder-promoting residues and can behave as intrinsically disordered proteins in aqueous conditions, with stress-mimicking environments promoting partial structuring and protective activity. Functional genetic analyses indicate that at least one Arabidopsis LEA6 member is required for robust tolerance to osmotic and salinity stress during germination and early seedling establishment, and is critical for maintaining seed longevity by supporting formation/maintenance of the low-mobility "glassy" cytoplasmic state associated with desiccation tolerance; loss of LEA6 compromises glass stability and accelerates viability decline during aging. Collectively, LEA6 proteins act as dehydration-associated protectants that help preserve cellular integrity under low-water availability, particularly in the seed context, likely by stabilizing macromolecules and biophysical properties of the intracellular milieu during drying and subsequent rehydration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AtLEA6-2.1; AtLEA6-2.2; AtLEA6-2.3; PvLEA18